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产品英文名称：StemRD W3A-H-025 WNT-3a,human,25ug
产品中文名称：StemRD W3A-H-025人源WNT-3a 蛋白因子，25ug
产品信息
Wnt糖蛋白是存在于多种生物体内的一种细胞外配体，Wnt作为形态发生素通过激发细胞内远离信号发送区域的浓度依赖反应控制胚胎形态发育。Wnt通路调节动物发育过程中的多个重要环节，例如细胞增殖、细胞迁徙及细胞分化。Wnt蛋白通过自分泌或旁分泌作用与位于细胞膜上的受体相结合，激活细胞内信号通路调节靶基因的表达，对细胞的增殖、分化、迁移、极性化和凋亡起到重要作用。
StemRD W3A-H-025B WNT-3a,human,25ug 产品简介
StemRD已研发出一种新颖的表达和纯化诸如StemRD W3A-H-025B WNT-3a,human,25ug 蛋白等“困难"蛋白的*方法。我们*的处理方法能得到纯度和活性均于市场方法生产的WNT蛋白。StemRD W3A-H-025B WNT-3a,human,25ug 蛋白绝不含有现今市场普遍使用的WNT蛋白中含有的某些非特异性成分。
WNT-3a 干细胞生长分化因子是WNT 信号蛋白家庭的成员之一，在胚胎成长和成体组织维护方面起关键作用。WNT-3a 干细胞生长分化因子是典型的通过β-联蛋白通路发送信号。已有规格的WNT-3a是一个包含328个氨基酸残基的单链蛋白质。由于糖基化，WNT-3a 在非还原条件下用SDS-PAGE处理会明显损失掉38-41 kDa分子量。StemRD公司生产的WNT-3a干细胞生长分化因子是用人体细胞系中Wnt-3a cDNA 在无蛋白培养基上过度表达得到。使用StemRD W3A-H-025B WNT-3a,human,25ug *的纯化方法，区别于其它已发表的纯化方法，提高蛋白纯度。
StemRD W3A-H-025B人源WNT-3a 蛋白因子，25ug 产品特性
»StemRD W3A-H-025B人源WNT-3a 蛋白因子，25ug 干细胞生长分化因子使用LC/MS 层析，纯度大于98%，结构经过NMR验证
»StemRD W3A-H-025B人源WNT-3a 蛋白因子，25ug 干细胞生长分化因子生物活性认证：经过生物试验验证，优于其它同类型产品
» WNT-3a 干细胞生长分化因子是典型的通过β-联蛋白通路发送信号
StemRD W3A-H-025B人源WNT-3a 蛋白因子，25ug 保存方法
The lyophilized protein is stable for at least 6 months if stored at -80 degreeC. Reconstituted protein is stable for at least two weeks at 4 degree C, but should be stored in aliquots at -80 degree C for longer term. Avoid repeated freeze and thaw.
StemRD W3A-H-025B WNT-3a,human,25ug 产品英文描述
We express and purify StemRD W3A-H-025B WNT-3a,human,25ug proteins by using a proprietary process that is distinctive from the published protocol. Our method results inStemRD W3A-H-025B WNT-3a,human,25ug proteins that are purer and more active than market-leading products which have been associated with non-specific artifacts.
WNT-3a is a member of the WNT family of signaling proteins that play key roles in embryonic development and the maintenance of adult tissues. WNT-3a is a prototypic canonical WNT that signals through the β-catenin pathway. The predicted size of human WNT-3a is a monomeric protein containing 328 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of 38 - 41 kDa on SDS-PAGE under non-reducing conditions. StemRD’s W3A-H-025B WNT-3a,human,25ug,is produced from a human cell line overexpressing human Wnt-3a cDNA in protein-free medium.Purification is done by a proprietary process that is distinct from the published method.
WNT all compounds are:
1. >98% pure by LC/MS analysis, and structurally verified by NMR.
2. Bioactivity Certified: tested for biological activities, an advent-age over other supplies.
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