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Anti-Human TRA-2-49 Antibody, Clone TRA-2-49/6E抗人TRA-2-49抗体产品信息:
The TRA-2-49/6E antibody reacts with the tissue non-specific isoform of alkaline phosphatase (AP), which is expressed at high levels in undifferentiated pluripotent stem cells such as human and mouse embryonic stem (ES) cells, as well as induced pluripotent stem (iPS) and embryonal carcinoma (EC) cells. This isozyme of AP is the same as that expressed by liver, bone and kidney cells. Levels of AP decrease upon differentiation and, thus, the TRA-2-49/6E antibody can be used to monitor the differentiation status of pluripotent stem cells. The TRA-2-49/6E antibody does not cross-react with other isozymes of AP, which differ through post-translational modification, and reportedly does not recognize AP from cow, dog, goat, Guinea pig, hamster, mouse, rat or sheep, or Old World Monkeys such as the rhesus monkey, baboon and African green monkey.
产品介绍:
Clone Name: TRA-2-49/6E
Species Reactivity: Cat, Human, Monkey, Non-human primate, Pig, Rabbit
Host Species: Mouse
Immunogen: Human embryonal carcinoma cell line 2102Ep
Isotype: IgG1, kappa
Application: Flow cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western blotting
Alternate Names: Liver/bone/kidney alkaline phosphatase, tissue non-specific alkaline phosphatase
Gene ID: 249
Product Type: Antibodies
Activity: 0.5 mg/mL
Antibody Type: Primary antibodies
Area of Interest: Embryonic stem cell & iPS cell research
Cell Type: Embryonic stem cells & iPS cells
Conjugation: Unconjugated
Legal Statement: Alexa Fluor® is a registered trademark of Life Technologies Corporation. This product is licensed for internal research use only and its sale is expressly conditioned on the buyer not using it for manufacturing, performing a service, or medical test, or otherwise generating revenue. For use other than research, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com.
Intended Use Statement: FOR RESEARCH USE ONLY. NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES.
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