Anti-ECSIT antibody （ab21288）抗ECSIT抗体

Anti-ECSIT antibody （ab21288）抗ECSIT抗体产品信息：

• Product nameAnti-ECSIT antibody
• Description

  Rabbit polyclonal to ECSIT

• Tested applicationsICC/IF, IP, IHC-P, WB
• Species reactivity

  Reacts with: Mouse, Human

• Immunogen

  Synthetic peptide corresponding to 14 amino acids near the C-terminus of ECSIT (Human).

• Positive control
  • human heart lysate

Properties

• FormLiquid
• Storage instructionsStore at +4°C.
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: PBS

• Concentration 100 µg at 1 mg/ml

• Purification notesIon exchange chromatography.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Signaling Pathway
  • Nuclear Signaling
  • NFkB Pathway
  • Immunology
  • Innate Immunity
  • TLR Signaling

Applications

Our Abpromise guarantee covers the use of ab21288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

• FunctionAdapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
• Sequence similaritiesBelongs to the ECSIT family.
• Cellular localizationCytoplasm. Nucleus. Mitochondrion.

• Database links

  • Entrez Gene: 51295 Human
  • Entrez Gene: 26940 Mouse
  • Omim: 608388 Human
  • SwissProt: Q9BQ95 Human
  • SwissProt: Q9QZH6 Mouse
  • Unigene: 515146 Human
  • Unigene: 425568 Mouse

• Alternative names

  • Ecsit antibody
  • ECSIT homolog antibody
  • ECSIT protein antibody

Anti-ECSIT antibody images

• 

  Western blot - ECSIT antibody (ab21288)

  Lane 1 : Anti-ECSIT antibody (ab21288) at 0.5 µg/ml
  Lane 2 : Anti-ECSIT antibody (ab21288) at 1 µg/ml
  Lane 3 : Anti-ECSIT antibody (ab21288) at 2 µg/ml
  
  Lane 1 : human heart lysate
  Lane 2 : human heart lysate
  Lane 3 : human heart lysate
  
  
  Predicted band size : 49 kDa
  Observed band size : 42 kDa (why is the actual band size different from the predicted?)

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ECSIT antibody (ab21288)

  ab21288 at 2µg/ml staining ECSIT in mouse heart by IHC

公司介绍：

    Abcam位于英国的剑桥科学园，成立于1998年，专门生产和分销研究型抗体。主要创立人Jonathan Milner和实验室同事构思成立一间了解科研人员需要的网上抗体公司，理念是Abcam销售质量高的抗体，并提供zui全面、诚实、时新的说明书，快速的送货服务，及高效率的顾客和服务。我们的在线目录(www.jiefang996.com) 已有差不多100,000种抗体和试剂，并不断添加，供应予百多个国家。Abcam于2005年11月在伦敦证券交易所上市，在美国马萨诸塞州、日本东京及香港均设有分公司。

    Abcam 一直致力加强产品线，为使研究员更容易找到蛋白质研究试剂产品，在2011并购了美国的MitoSciences公司，加强了免疫分析方面的产品供应；同年也并购了英国的Ascent Scientific 公司，开展了生化试剂的供应。在2012年，Abcam并购了美国的Epitomics 公司，成为一家有的RabMAbs® 供应商。

    Abcam 的 目标是给世界上的抗体建立zui大的在线目录，为各地科学家提供*产品，成为各国科学界的重要伙伴。我们为所有产品提供来使客户获得预期的结 果。为提供高质量的抗体来指向尽可能多的靶蛋白，我们尽所能在尽可能多的应用和物种中检测每种抗体。我们相信诚信才是上策，在我们的上会发布有关我们 每一种产品的尽可能多的信息。

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